Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059903 | 1.00 | PPARA (0.34) | PPARAALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL11068125 | 0.93 | PPARA (0.41) | PPARAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11067293 | 0.89 | MAPT (0.33) | PPARAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11067295 | 0.89 | MAPT (0.33) | PPARAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11299113 | 0.81 | CNR1 (0.38) | PPARAKDM4ERAB9ACYP1A2FAAH | |
| SCHEMBL11502963 | 0.77 | CYP3A4 (0.36) | PPARAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11067539 | 0.75 | AKR1C3 (0.51) | PPARAALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL11067526 | 0.75 | AKR1C3 (0.51) | PPARAALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL11068468 | 0.74 | SOAT2 (0.47) | PPARAKDM4EMAPTHDAC8HDAC11 | |
| SCHEMBL11068475 | 0.74 | SOAT2 (0.47) | PPARAKDM4EMAPTHDAC8HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |