Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 17/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 10/20 | 0.60 |
| ▸ | PTGER2 | P43116 | 10/20 | 0.60 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060037 | 1.00 | PTGER4 (0.60) | PTGER4PTGER3PTGER2GALR3KCNH2 | |
| SCHEMBL11062129 | 0.86 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11062131 | 0.86 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11830503 | 0.75 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11830499 | 0.75 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11067995 | 0.74 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11067999 | 0.74 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11662045 | 0.73 | PTGER4 (0.77) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL5214584 | 0.71 | PTGER4 (0.94) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5214403 | 0.71 | PTGER4 (0.94) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456613-A | 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-26 | — | — | US | disclosed |