Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.94 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.94 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214584 | 1.00 | PTGER4 (0.94) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214409 | 1.00 | PTGER4 (0.94) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5183543 | 0.97 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2446214 | 0.97 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2446210 | 0.97 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2446235 | 0.97 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5217330 | 0.94 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5217323 | 0.94 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214140 | 0.94 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL11830499 | 0.89 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | claimed |
| US-6849657-B2 | 2-pyrrolidone derivatives as prostanoid agonists | SYNTEX (U.S.A.) LLC (US) | 2005-02-01 | — | — | US | claimed |
| US-20030064964-A1 | 2-pyrrolidone derivatives as prostanoid agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-04-03 | — | — | US | claimed |
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | disclosed |
| US-6849657-B2 | 2-pyrrolidone derivatives as prostanoid agonists | SYNTEX (U.S.A.) LLC (US) | 2005-02-01 | — | — | US | disclosed |
| US-20030064964-A1 | 2-pyrrolidone derivatives as prostanoid agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064964-A1 | 2-pyrrolidone derivatives as prostanoid agonists | PTGER1, PTGER4, PTGIR | PTGER4 2/4885PTGER2 4/4885PTGER3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.