Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 15/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062421 | 0.82 | PDE3B (0.66) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11314216 | 0.80 | PDE3B (0.66) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11062167 | 0.77 | PDE3B (0.57) | PDE3BPDE3A | |
| SCHEMBL11064841 | 0.77 | PDE3B (0.42) | PDE3BPDE3AHRH3P2RY12 | |
| SCHEMBL11071221 | 0.76 | PDE3B (0.56) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11067561 | 0.74 | PDE3B (0.40) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11323200 | 0.74 | TRIM24 (0.46) | PDE3BPDE3ATRIM24P2RY12 | |
| SCHEMBL11062238 | 0.74 | PDE3B (0.48) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9036841 | 0.73 | PDE3B (0.62) | PDE3BPDE3AP2RY12 | |
| SCHEMBL9036166 | 0.73 | PDE3B (0.39) | PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |