Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 13/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067561 | 0.79 | PDE3B (0.40) | PDE3BPDE3APDE2AP2RY12 | |
| Oxalic Acid SCHEMBL9036161 | 0.79 | PDE3B (0.59) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL9035670 | 0.75 | PDE3B (0.41) | PDE3BPDE3AMAOAMAOBPDE2A | |
| SCHEMBL9035070 | 0.75 | PDE3B (0.41) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9035287 | 0.75 | PDE3B (0.61) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11060120 | 0.73 | PDE3B (0.43) | PDE3BPDE3AP2RY12 | |
| SCHEMBL9283568 | 0.71 | PDE3B (0.58) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11067264 | 0.70 | PDE3B (0.63) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL9035659 | 0.70 | MEN1 (0.36) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11067800 | 0.69 | PDE3B (0.62) | PDE3BPDE3AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |