Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681370 | 1.00 | ATM (0.57) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL14777782 | 1.00 | ATM (0.57) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL10584682 | 0.93 | ATM (0.50) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL472781 | 0.92 | ATM (0.49) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL37109 | 0.91 | ATM (0.47) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL23149462 | 0.90 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL28423365 | 0.87 | ATM (0.43) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL16680650 | 0.87 | ATM (0.43) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL1132928 | 0.86 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL93561 | 0.86 | TSHR (0.59) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310792-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORP (US) | 2021-07-21 | — | — | EP | claimed |
| EP-3310793-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORP (US) | 2021-06-09 | — | — | EP | claimed |
| CN-107743493-B | Process for preparing acryloxysilanes | 美国陶氏有机硅公司 | 2020-10-30 | — | — | CN | claimed |
| CN-107743492-B | Process for preparing acryloxysilanes | 美国陶氏有机硅公司 | 2020-07-17 | — | — | CN | claimed |
| EP-3653673-A1 | ORGANOSILANE-MODIFIED PRECIPITATED SILICA | RHODIA OPERATIONS (FR) | 2020-05-20 | — | — | EP | claimed |
| US-10273254-B2 | Process for preparing an acryloyloxysilane | DOW CORNING CORPORATION (US) | 2019-04-30 | — | — | US | claimed |
| US-10246473-B2 | Process for preparing an acryloyloxysilane | DOW CORNING CORPORATION (US) | 2019-04-02 | — | — | US | claimed |
| US-20180155371-A1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORPORATION | 2018-06-07 | — | — | US | claimed |
| US-20180134734-A1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORPORATION | 2018-05-17 | — | — | US | claimed |
| EP-3310793-A1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | Dow Corning Corporation (US) | 2018-04-25 | — | — | EP | claimed |
| US-9249164-B2 | Process for preparing an acryloyloxysilane | DOW SILICONES CORPORATION | 2016-02-02 | — | — | US | claimed |
| EP-2621936-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW CORNING (US) | 2014-10-22 | — | — | EP | claimed |
| US-20140031487-A1 | EPOXIDISED ELASTOMER COMPOSITIONS MODIFIED BY SILANES | RHODIA OPERATION (FR) | 2014-01-30 | — | — | US | claimed |
| US-8580886-B2 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | DOW CORNING CORPORATION (US) | 2013-11-12 | — | — | US | claimed |
| EP-2424740-B1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | DOW CORNING (US) | 2013-10-16 | — | — | EP | claimed |
| US-20130184482-A1 | Process For Preparing An Acryloyloxysilane | DOW CORNING CORPORATION (US) | 2013-07-18 | — | — | US | claimed |
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | DOW CORNING CORPORATION (US) | 2013-03-21 | — | — | US | claimed |
| US-20120059121-A1 | Elastomer Compositions Modified By Silanes | DOW CORNING EUROPE SA (BE) | 2012-03-08 | — | — | US | claimed |
| EP-2424740-A1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | Dow Corning Corporation (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010125123-A1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | DOW CORNING CORPORATION (US) | 2010-11-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | PBRM1, IPMK, BOLA2; BOLA2B | ATM 1782/4885HCAR2 1876/4885MAPT 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.