SCHEMBL16680650

SCHEMBL16680650

CC=CC=CC(=O)OCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
HCAR2 Q8TDS4 5/20 0.39
MAPT P10636 2/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
TSHR P16473 2/20 0.34
HPGD P15428 1/20 0.34
APP P05067 2/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28423365 1.00 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL37109 0.89 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL14777782 0.87 ATM (0.57) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL110602 0.87 ATM (0.57) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL16681370 0.87 ATM (0.57) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1132928 0.84 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL728878 0.84 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL12445250 0.84 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL25317040 0.83 HCAR2 (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL25317335 0.83 HCAR2 (0.45) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
EP-3310793-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-06-09 EP claimed
US-10273254-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-30 US claimed
US-10246473-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-02 US claimed
US-20180155371-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-06-07 US claimed
US-20180134734-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-05-17 US claimed
EP-3310793-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP claimed
EP-3310792-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP claimed
WO-2016205642-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO claimed
WO-2016205648-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO claimed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP disclosed
EP-3310793-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-06-09 EP disclosed
US-10273254-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-30 US disclosed
US-10246473-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-02 US disclosed
EP-2785726-B1 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS DOW SILICONES CORP (US) 2018-08-01 EP disclosed
EP-3310793-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP disclosed
WO-2016205648-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
WO-2016205642-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
US-9518072-B2 Ester-functional silanes and the preparation and use thereof; and use of iminium compounds as phase transfer catalysts DOW CORNING CORPORATION (US) 2016-12-13 US disclosed
US-20150126676-A1 Ester-Functional Silanes And The Preparation And Use Thereof; And Use Of Iminium Compounds As Phase Transfer Catalysts DOW SILICONES CORPORATION 2015-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126676-A1 Ester-Functional Silanes And The Preparation And Use Thereof; And Use Of Iminium Compounds As Phase Transfer Catalysts ICMT, INTS9, HDHD5 ATM 2209/4885HCAR2 2989/4885MAPT 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.