Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077421 | 0.98 | HPGD (0.42) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL11151481 | 0.87 | MEN1 (0.40) | ALDH1A1HPGDNPC1MEN1KMT2A | |
| SCHEMBL5303512 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL25447805 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL8014381 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL1140476 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL10223269 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL7246527 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL21455835 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL5518645 | 0.80 | HPGD (0.43) | ALDH1A1HTTMMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |
| US-4457931-A | ANTISPASMODIC | SELVI & C. S.P.A. (IT) | 1984-07-03 | — | — | US | disclosed |