Questiomycin B

Questiomycin B

SCHEMBL11060308

Nc1ccccc1O.O=C1C=CC(=O)C=C1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.71
TSHR P16473 2/20 0.71
DBH P09172 2/20 0.42
MMP2 P08253 1/20 0.42
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 5/20 0.41
HPGD P15428 4/20 0.41
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
POLB P06746 3/20 0.41
BLM P54132 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
KDM4E B2RXH2 3/20 0.41
CYP3A4 P08684 3/20 0.41
LMNA P02545 2/20 0.41
CASP1 P29466 2/20 0.41
APEX1 P27695 2/20 0.41
RECQL P46063 2/20 0.41
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Questiomycin B SCHEMBL3999786 0.84 ALOX15 (1.00) ALOX15TSHRMMP2ALDH1A1HSD17B10
Questiomycin B SCHEMBL24436 0.84
Questiomycin B SCHEMBL29430322 0.84
Questiomycin B SCHEMBL1823522 0.82 ALOX15 (0.83) ALOX15TSHRDBHMMP2ALDH1A1
Benzoquinone SCHEMBL28499021 0.82 CYP3A4 (0.62) ALOX15TSHRALDH1A1HSD17B10HPGD
Questiomycin B SCHEMBL11412866 0.82
SCHEMBL18612812 0.82 ALOX15 (0.94) ALOX15TSHRDBHMMP2ALDH1A1
Questiomycin B SCHEMBL4747619 0.82 ALOX15 (0.94) ALOX15TSHRMMP2ALDH1A1HSD17B10
Questiomycin B SCHEMBL3887270 0.82
Questiomycin B SCHEMBL15436150 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4461827-A Color photographic recording material containing a non-diffusible dye releaser from which a complexible azo dye is released during development AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1984-07-24 US disclosed