SCHEMBL11060360

SCHEMBL11060360

NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.61
ACE P12821 10/20 0.61
ACE2 Q9BYF1 7/20 0.61
TSHR P16473 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30165330 0.96 ACE (0.57) LTA4HACEACE2TSHR
SCHEMBL5710967 0.92 ACE (0.61) LTA4HACEACE2TSHR
SCHEMBL5030487 0.92 ACE (0.54) LTA4HACEACE2TSHR
SCHEMBL5030497 0.92 ACE (0.54) LTA4HACEACE2TSHR
SCHEMBL30358542 0.91 ACE (0.58) LTA4HACEACE2TSHR
SCHEMBL29630391 0.91 ACE (0.55) LTA4HACEACE2TSHR
SCHEMBL5030820 0.89 ACE (0.53) LTA4HACEACE2TSHR
SCHEMBL5030837 0.89 ACE (0.53) LTA4HACEACE2TSHR
SCHEMBL8279537 0.88 ACE (0.61) LTA4HACEACE2TSHR
SCHEMBL8258582 0.88 ACE (0.61) LTA4HACEACE2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113583087-B Spirulina immune active peptide and preparation method and application thereof 北京林业大学 2022-07-08 CN claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
CN-113583087-B Spirulina immune active peptide and preparation method and application thereof 北京林业大学 2022-07-08 CN disclosed
CN-113583087-B Spirulina immune active peptide and preparation method and application thereof 北京林业大学 2022-07-08 CN disclosed
US-4465625-A ANALGESICS RICHTER GEDEON VEGYESZETI GYAR (HU) 1984-08-14 US disclosed
US-4288432-A ANALGESICS RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1981-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP LTA4H 3533/4885ACE 1190/4885ACE2 1622/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD LTA4H 1299/4885ACE 486/4885ACE2 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.