Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809624 | 0.94 | BCL2 (0.50) | BCL2MAOAMAOBCDK5CDK5R1 | |
| SCHEMBL11695692 | 0.87 | KDR (0.41) | BCL2MAOAMAOBKDRCDK5 | |
| SCHEMBL11674909 | 0.82 | BCL2 (0.59) | BCL2MAOAMAOBMCL1BCL2L11 | |
| SCHEMBL10952664 | 0.80 | KDR (0.48) | KDRCDK5CDK5R1KDM4EPOLB | |
| SCHEMBL11633105 | 0.79 | ADORA2A (0.41) | BCL2MAOAMAOBKDRCDK5 | |
| Trifluoromethanesulfonic Acid SCHEMBL17726790 | 0.77 | BCL2 (0.51) | BCL2MAOAMAOBMCL1BCL2L11 | |
| SCHEMBL21501553 | 0.75 | BCL2 (0.62) | BCL2MAOAMAOBMCL1BCL2L11 | |
| SCHEMBL17726858 | 0.74 | BCL2 (0.48) | BCL2MAOAMAOBMCL1BCL2L11 | |
| SCHEMBL11346047 | 0.74 | BCL2 (0.60) | BCL2MCL1BCL2L11BCL2L1KDM4E | |
| SCHEMBL7307793 | 0.74 | CDK5 (0.54) | KDRCDK5CDK5R1RORCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451398-A | Dyes containing imidazolymethylene groups | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |
| US-4268668-A | FOR WOOL AND POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| EP-0025936-A1 | Naphtholactam derivatives and their use as dyestuffs | BASF Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | disclosed |
| US-4096145-A | DYES FOR RESINS AND POLYESTER TEXTILES | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3963747-A | Basic arylmercaptonaphtholactam dyes | BASF AKTIENGESELLSCHAFT (DT) | 1976-06-15 | — | — | US | disclosed |