Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | CASP1 | P29466 | 5/20 | 0.44 |
| ▸ | CASP7 | P55210 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307793 | 0.94 | CDK5 (0.54) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL11060440 | 0.80 | BCL2 (0.50) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL11695692 | 0.79 | KDR (0.41) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL9450641 | 0.77 | CDK5 (0.50) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL9450598 | 0.77 | KDM4E (0.53) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL9450628 | 0.75 | KDM4E (0.52) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL11689659 | 0.75 | USP2 (0.74) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL8482582 | 0.75 | KDR (0.48) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL8796831 | 0.75 | KDM4E (0.51) | KDRCDK5CDK5R1KDM4EALDH1A1 | |
| SCHEMBL29532065 | 0.75 | KDR (0.48) | KDRCDK5CDK5R1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529804-A | Naphthostyril Ni or Cu complexes, a process for their preparation, and high molecular weight organic material pigmented with these metal complexes | CIBA-GEIGY CORPORATION (US) | 1985-07-16 | — | — | US | disclosed |
| US-4246422-A | Naphtholactam dyestuffs | CIBA-GEIGY AG (CH) | 1981-01-20 | — | — | US | disclosed |
| US-4146541-A | YELLOW SHADE ON POLYESTERS | CIBA-GEIGY AG (CH) | 1979-03-27 | — | — | US | disclosed |