Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | INMT | O95050 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19345926 | 0.73 | BRD4 (0.48) | BRD4BRD2MEN1KMT2AMAPT | |
| SCHEMBL16492022 | 0.70 | BRD4 (0.44) | BRD4BRD2MEN1KMT2AMAPT | |
| Undecane SCHEMBL28268300 | 0.69 | BRD4 (0.61) | BRD4BRD2MEN1KMT2AMAPT | |
| SCHEMBL14428797 | 0.69 | BRD4 (0.52) | BRD4BRD2MEN1KMT2AMAPT | |
| SCHEMBL120927 | 0.67 | — | — | |
| SCHEMBL1626056 | 0.66 | BRD4 (0.80) | BRD4BRD2MEN1KMT2AMAPT | |
| SCHEMBL54926 | 0.66 | — | — | |
| SCHEMBL6885804 | 0.66 | BRD4 (0.80) | BRD4BRD2MEN1KMT2AMAPT | |
| SCHEMBL329328 | 0.66 | BRD4 (0.80) | BRD4BRD2MEN1KMT2AMAPT | |
| SCHEMBL14747422 | 0.66 | BRD4 (0.80) | BRD4BRD2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463177-A | Process for making m-hydroxyphenyl substituted compounds | JOHN WYETH & BROTHER LIMITED (GB) | 1984-07-31 | — | — | US | claimed |