Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.80 |
| ▸ | BRD2 | P25440 | 1/20 | 0.80 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | INMT | O95050 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300693 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| SCHEMBL26047692 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| SCHEMBL26047696 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| SCHEMBL6886758 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| SCHEMBL1626056 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| SCHEMBL329328 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| SCHEMBL26047693 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| SCHEMBL54926 | 1.00 | — | — | |
| SCHEMBL6885804 | 1.00 | BRD4 (0.80) | BRD4BRD2ACHEINMTMAPT | |
| Hydrochloric Acid SCHEMBL17238240 | 0.97 | BRD4 (0.76) | BRD4BRD2ACHEINMTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265080-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMA (US) | 2023-08-24 | — | — | US | disclosed |
| US-20230232830-A1 | METHOD FOR REDUCING OR PREVENTING EFFECT OF NON-BIOLOGICAL STRESS ON PLANT | NIPPON SODA CO., LTD. (JP) | 2023-07-27 | — | — | US | disclosed |
| WO-2020081257-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-04-23 | — | — | WO | disclosed |
| US-8389536-B2 | Positive allosteric modulators (PAM) | HOFFMANN-LA ROCHE INC. (US) | 2013-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230232830-A1 | METHOD FOR REDUCING OR PREVENTING EFFECT OF NON-BIOLOGICAL STRESS ON PLANT | NFE2L2, TXN, GPX1 | BRD4 1144/4885BRD2 1271/4885ACHE 1550/4885 |
| US-20230265080-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | SERPINA2, SERPINA3, SERPINB1 | BRD4 2882/4885BRD2 2755/4885ACHE 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.