Oleamide

Oleamide

SCHEMBL11060798

CCCCCCCCC=CCCCCCCCC(N)=O.CCCCOP(=O)(O)OCCCC

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.68
FAAH O00519 2/20 0.68
MEN1 O00255 1/20 0.68
TP53 P04637 1/20 0.68
CYP1A2 P05177 1/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2C19 P33261 1/20 0.68
KMT2A Q03164 1/20 0.68
KDM4E B2RXH2 2/20 0.62
P2RY10 O00398 5/20 0.59
GPR34 Q9UPC5 1/20 0.59
LPAR3 Q9UBY5 2/20 0.58
LPAR1 Q92633 2/20 0.56
LPAR2 Q9HBW0 2/20 0.56
CNR1 P21554 1/20 0.55
ENPP2 Q13822 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleamide SCHEMBL11081568 0.97 SOAT1 (0.68) SOAT1FAAHMEN1TP53CYP1A2
SCHEMBL2183943 0.88 LPAR3 (0.72) P2RY10GPR34LPAR3LPAR1LPAR2
SCHEMBL8657648 0.88 LPAR3 (0.72) P2RY10GPR34LPAR3LPAR1LPAR2
Oleamide SCHEMBL11077328 0.87 FAAH (0.66) SOAT1FAAHMEN1TP53CYP1A2
Oleamide SCHEMBL7596970 0.86 FAAH (0.85) SOAT1FAAHMEN1TP53CYP1A2
SCHEMBL6120935 0.86 LPAR3 (0.74) P2RY10GPR34LPAR3LPAR1LPAR2
Oleamide SCHEMBL7596963 0.86 FAAH (0.85) SOAT1FAAHMEN1TP53CYP1A2
SCHEMBL6316146 0.86 LPAR3 (0.74) P2RY10GPR34LPAR3LPAR1LPAR2
SCHEMBL145057 0.86 LPAR3 (0.74) P2RY10GPR34LPAR3LPAR1LPAR2
SCHEMBL158207 0.86 LPAR3 (0.74) P2RY10GPR34LPAR3LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4472288-A EXTREME PRESSURE, STABILIZERS, CRYSTAL GROWTH INHIBITORS CHEVRON RESEARCH COMPANY (US) 1984-09-18 US claimed
US-4459215-A EXTREME PRESSURE LUBRICANTS CHEVRON RESEARCH COMPANY (US) 1984-07-10 US claimed
US-4431552-A EXTREME PRESSURE LUBRICANTS; WEAR RESISTANCE CHEVRON RESEARCH COMPANY (US) 1984-02-14 US claimed
US-4472288-A EXTREME PRESSURE, STABILIZERS, CRYSTAL GROWTH INHIBITORS CHEVRON RESEARCH COMPANY (US) 1984-09-18 US disclosed
US-4431552-A EXTREME PRESSURE LUBRICANTS; WEAR RESISTANCE CHEVRON RESEARCH COMPANY (US) 1984-02-14 US disclosed