Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147945 | 1.00 | SRC (0.69) | SRCTSHRALDH1A1NT5EPTPN1 | |
| SCHEMBL11147051 | 0.82 | SRC (0.47) | SRCTSHRALDH1A1NT5EPTPN1 | |
| SCHEMBL11147045 | 0.82 | SRC (0.47) | SRCTSHRALDH1A1NT5EPTPN1 | |
| SCHEMBL7898010 | 0.82 | SRC (1.00) | SRCALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL11166146 | 0.81 | SRC (1.00) | SRCALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL9912818 | 0.81 | SRC (1.00) | SRCALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL20869602 | 0.81 | SRC (1.00) | SRCALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL6381902 | 0.80 | SRC (0.96) | SRCALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL28406293 | 0.79 | SRC (0.96) | SRCALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL5016643 | 0.79 | SRC (0.96) | SRCALDH1A1PTPN1PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467101-A | CEPHALOSPORIN PRECURSORS | CIBA-GEIGY CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| US-4374134-A | Cephalosporin compounds with terminal aminocarboxylic acid groupings and anti-bacterial use thereof | CIBA-GEIGY CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |