Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381902 | 0.98 | SRC (0.96) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL9912818 | 0.83 | SRC (1.00) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL20869602 | 0.83 | SRC (1.00) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL11166146 | 0.83 | SRC (1.00) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL11211519 | 0.82 | SRC (0.69) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL11147945 | 0.82 | SRC (0.69) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL11060902 | 0.82 | SRC (0.69) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL11211513 | 0.82 | SRC (0.69) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL5016643 | 0.81 | SRC (0.96) | SRCLMNAPTPN1PTPN6PTPN11 | |
| SCHEMBL28406293 | 0.81 | SRC (0.96) | SRCLMNAPTPN1PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313247-B1 | Cinchonan based chiral selectors for separation of stereoisomers | LINDNER WOLFGANG (AT) | 2001-11-06 | — | — | US | disclosed |
| US-4244885-A | α-Substituted-3-(halomethyl)-4-hydroxybenzeneacetic acids | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1981-01-13 | — | — | US | disclosed |
| US-4236002-A | ANTIBIOTICS | YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) | 1980-11-25 | — | — | US | disclosed |
| US-4229363-A | INTERMEDIATES FOR CEPHALOSPORIN AND PENICILLIN DERIVATIVES | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1980-10-21 | — | — | US | disclosed |
| US-4197240-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1980-04-08 | — | — | US | disclosed |