Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CDC25B | P30305 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578128 | 0.87 | TSHR (0.77) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| Diethyl Phthalate SCHEMBL7520316 | 0.85 | TSHR (0.95) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| Diethyl Phthalate SCHEMBL27742347 | 0.85 | TSHR (0.95) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| SCHEMBL7670783 | 0.84 | TSHR (0.71) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL7669334 | 0.84 | TSHR (0.71) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| Diethyl Phthalate SCHEMBL5306972 | 0.82 | TSHR (1.00) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| Diethyl Phthalate SCHEMBL22296 | 0.82 | TSHR (1.00) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| Diethyl Phthalate SCHEMBL29404255 | 0.82 | TSHR (1.00) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| SCHEMBL5713410 | 0.82 | TSHR (0.69) | TSHRHSD17B10ALDH1A1CDC25BCA12 | |
| SCHEMBL3022732 | 0.82 | TSHR (0.69) | TSHRHSD17B10ALDH1A1CDC25BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443475-A | ANTIARRHYTHMIA AGENTS, ANTIDEPRESSANTS | CAVAZZA CLAUDIO (IT) | 1984-04-17 | — | — | US | claimed |