Diethyl Phthalate

Diethyl Phthalate

SCHEMBL29404255

CCOC(=O)c1ccccc1C(=O)OCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 1.00
ALDH1A1 P00352 4/20 0.74
HSD17B10 Q99714 3/20 0.74
CDC25B P30305 2/20 0.66
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CYP3A4 P08684 2/20 0.62
TP53 P04637 1/20 0.62
MAPK1 P28482 1/20 0.62
LMNA P02545 2/20 0.60
KDM4E B2RXH2 2/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
KMT2A Q03164 2/20 0.56
CDC25A P30304 1/20 0.56
CDC25C P30307 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethyl Phthalate SCHEMBL5306972 1.00 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL22296 1.00 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL27321495 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL8577506 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL28335913 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL30925693 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL30120741 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL19252611 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL7520316 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL28775845 0.98 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240280590-A1 COMPOSITIONS AND METHODS FOR FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY BIOMARKER DETECTION UNIVERSITY OF WASHINGTON (US) 2024-08-22 US disclosed
CN-118251508-A Protein-containing composition and method for rare earth element separation 劳伦斯利弗莫尔国家安全有限责任公司 2024-06-25 CN disclosed
EP-4137167-A1 CORNEAL IMPLANTS FOR TREATING ECTATIC CORNEAL DISEASE RVO 2.0, Inc. D/B/A Optics Medical (US) 2023-02-22 EP disclosed
CN-115356308-A Method for high-throughput detection of phthalic acid ester based on molecularly imprinted quantum dot fluorescent probe 宁波大学 2022-11-18 CN disclosed
US-11254783-B2 Xylylenediisocyanate composition, xylylenediisocyanate-modified composition, two-component resin material, and resin MITSUI CHEMICALS, INC. (JP) 2022-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11254783-B2 Xylylenediisocyanate composition, xylylenediisocyanate-modified composition, two-component resin material, and resin DCXR, SULT1E1, YTHDC1 TSHR 4751/4885ALDH1A1 1627/4885HSD17B10 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.