Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061030 | 0.89 | ABL1 (0.50) | ABL1GAAPDE5APRKCZKMT2A | |
| SCHEMBL11054662 | 0.87 | ABL1 (0.74) | ABL1GAAPDE5A | |
| SCHEMBL11060498 | 0.86 | ABL1 (0.48) | ABL1GAAPDE5AHDAC6 | |
| SCHEMBL11058884 | 0.86 | PDE5A (0.51) | PDE5APRKCZKMT2AMEN1ATM | |
| SCHEMBL11068634 | 0.85 | ABL1 (0.47) | ABL1GAAPDE5AKMT2AMAPT | |
| SCHEMBL11061067 | 0.84 | ABL1 (0.74) | ABL1PDE5APRKCZKMT2AMAPT | |
| SCHEMBL11063665 | 0.83 | MEN1 (0.49) | GAAPDE5APRKCZKMT2AMEN1 | |
| SCHEMBL11093164 | 0.80 | ABL1 (0.45) | ABL1PDE5APRKCZ | |
| SCHEMBL11091186 | 0.77 | ABL1 (0.43) | ABL1PDE5APRKCZFFAR1ALDH1A1 | |
| SCHEMBL11092462 | 0.77 | ABL1 (0.49) | ABL1PDE5APRKCZKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | claimed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| US-4448973-A | ANTIINFLAMMATORY, ANALGESIC AGENTS; BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |