SCHEMBL11061545

SCHEMBL11061545

Cc1c(O)c(C(C)C)cc(C(C)C)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
GABRA1 P14867 7/20 0.54
GABRB1 P18505 5/20 0.54
GABRB2 P47870 4/20 0.54
LMNA P02545 3/20 0.46
SLC6A2 P23975 2/20 0.46
HTR2B P41595 2/20 0.46
FAAH O00519 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
GABRG2 P18507 1/20 0.46
PTGS1 P23219 1/20 0.46
HTR2C P28335 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22645746 0.84 CA1 (0.54) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL16605720 0.84 CA1 (0.54) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL4907907 0.82 CA1 (0.52) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL11702760 0.80 CA1 (0.50) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL24925096 0.79 CA1 (0.48) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL544651 0.78 CA1 (0.67) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL6681495 0.78 CA1 (0.59) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL1244520 0.77 GABRA1 (0.48) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL17323097 0.77 CA1 (0.81) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL16789571 0.76 GABRA1 (0.56) CA1CA2GABRA1GABRB1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4021243-A Diazo light-sensitive copying composition and process of using in the manufacture of screen printing stencils HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-03 US claimed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed
US-4144067-A DIAZO RESIN, FISH GLUE BINDER HOECHST AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed