SCHEMBL11061590

SCHEMBL11061590

C=Cc1ccccc1CC.CCNc1cccc2cc3ccccc3cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
RAB9A P51151 2/20 0.38
MITF O75030 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
MAPK1 P28482 1/20 0.38
CCR6 P51684 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
LMNA P02545 1/20 0.35
KCNH2 Q12809 2/20 0.34
CACNA1C Q13936 2/20 0.34
SCN5A Q14524 2/20 0.34
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10624009 0.87 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL11066256 0.84 KMT2A (0.39) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL28147807 0.82 ALDH1A1 (0.50) MEN1KMT2AALDH1A1MAPTRAB9A
Styrene SCHEMBL10628559 0.81 MAPT (0.40) MEN1KMT2AALDH1A1MAPTRAB9A
Naphthalene SCHEMBL28223152 0.75 ALDH1A1 (0.40) MEN1KMT2AALDH1A1MAPTCYP1A2
SCHEMBL6849255 0.75 ALDH1A1 (0.43) MEN1KMT2AALDH1A1MAPTNPSR1
SCHEMBL10558460 0.74 SIRT2 (0.43) MEN1KMT2AALDH1A1CYP1A2CYP2C9
SCHEMBL8590907 0.73 ALDH1A1 (0.41) MEN1KMT2AALDH1A1MAPTNPSR1
SCHEMBL14959 0.73 ALDH1A1 (0.44) MEN1KMT2AALDH1A1MAPTNPSR1
SCHEMBL29749448 0.73 ALDH1A1 (0.44) MEN1KMT2AALDH1A1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473630-A Liquid developer comprising aminoalkyl styrene polymer for electrostatic images FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed