Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.56 |
| ▸ | MME | P08473 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864412 | 1.00 | ACE (0.56) | ACEMMENPSR1XIAPF7 | |
| SCHEMBL7864413 | 1.00 | ACE (0.56) | ACEMMENPSR1XIAPF7 | |
| SCHEMBL11067510 | 0.92 | ACE (0.55) | ACEMMENPSR1XIAPF7 | |
| SCHEMBL7872618 | 0.92 | ACE (0.47) | ACEMMENPSR1XIAPPREP | |
| SCHEMBL7872616 | 0.92 | ACE (0.47) | ACEMMENPSR1XIAPPREP | |
| SCHEMBL10855859 | 0.89 | ACE (0.52) | ACEMMEXIAPF7F3 | |
| SCHEMBL10855731 | 0.89 | ACE (0.52) | ACEMMEXIAPF7F3 | |
| SCHEMBL10851201 | 0.85 | ACE (0.51) | ACEMMENPSR1XIAP | |
| SCHEMBL10851205 | 0.85 | ACE (0.51) | ACEMMENPSR1XIAP | |
| SCHEMBL8837702 | 0.83 | ACE (0.67) | ACEMMEXIAPF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477464-A | Hetero-benzazepine derivatives and their pharmaceutical use | CIBA-GEIGY CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |