Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.81 |
| ▸ | MAOA | P21397 | 11/20 | 0.54 |
| ▸ | MAOB | P27338 | 11/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067324 | 0.87 | PDE3B (0.84) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11064324 | 0.87 | PDE3B (0.69) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11067644 | 0.86 | PDE3B (0.68) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11067554 | 0.84 | PDE3B (0.73) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11327684 | 0.83 | PDE3B (0.66) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11061330 | 0.83 | PDE3B (0.69) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11319861 | 0.82 | PDE3B (0.67) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11068183 | 0.80 | PDE3B (0.70) | PDE3BPDE3A | |
| SCHEMBL11064549 | 0.80 | MAOA (0.62) | PDE3BPDE3AMAOAMAOBDRD2 | |
| SCHEMBL11065691 | 0.79 | PDE3B (0.71) | PDE3BPDE3AMAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |