Morpholine

Morpholine

SCHEMBL11061823

C1COCCN1.CCOc1ccc(OCC)c([N+]#N)c1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
HPGD P15428 4/20 0.36
KDM4E B2RXH2 5/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
HSD17B10 Q99714 2/20 0.36
ADRB2 P07550 1/20 0.35
HTR1A P08908 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2A P28223 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
HTR2B P41595 1/20 0.35
SLC6A3 Q01959 1/20 0.35
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
FKBP1A P62942 1/20 0.34
KMT2A Q03164 2/20 0.34
RAD52 P43351 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL11060517 0.88 ALDH1A1 (0.38) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
Morpholine SCHEMBL10825057 0.87 ALDH1A1 (0.40) ALDH1A1HPGDKDM4ESMN1; SMN2HTR2A
SCHEMBL11230396 0.84 NQO1 (0.46) ALDH1A1HPGDKDM4EHSD17B10TSHR
Morpholine SCHEMBL10825052 0.83 ALDH1A1 (0.37) ALDH1A1HPGDSMN1; SMN2HTR2AHTR2B
Hydrochloric Acid SCHEMBL9138523 0.83 NQO1 (0.45) ALDH1A1HPGDKDM4EHSD17B10TSHR
Morpholine SCHEMBL11044415 0.80 SMN1; SMN2 (0.46) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL11411982 0.79 KDM4E (0.43) ALDH1A1KDM4EHSD17B10TSHRLMNA
1,4-Diethoxybenzene SCHEMBL10980721 0.78 NQO1 (0.52) ALDH1A1HPGDKDM4ESMN1; SMN2TSHR
Morpholine SCHEMBL10825062 0.76 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2SLC6A2SLC6A4SLC6A3
Trifluoromethanesulfonic Acid SCHEMBL11086410 0.76 TSHR (0.41) ALDH1A1TSHRHTTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482489-A USEFUL IN DIAZOTYPE SYSTEMS AND AS LATENT POLYMERIZATION INITIATORS JAMES RIVER GRAPHICS, INC. (US) 1984-11-13 US disclosed