Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23549 | 0.86 | TSHR (0.52) | TSHRCYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL23548 | 0.86 | TSHR (0.52) | TSHRCYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL10897591 | 0.81 | TSHR (0.42) | TSHRCYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL11427704 | 0.79 | TSHR (0.47) | TSHRCYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL11427707 | 0.79 | TSHR (0.47) | TSHRCYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL10898803 | 0.72 | TSHR (0.42) | TSHRCYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL1252396 | 0.72 | ALDH1A1 (0.31) | TSHR | |
| SCHEMBL1252394 | 0.72 | ALDH1A1 (0.31) | TSHR | |
| SCHEMBL9578042 | 0.71 | CYP2D6 (0.41) | TSHRCYP2D6CYP2C9CYP2C19GAA | |
| SCHEMBL11689846 | 0.71 | CYP2D6 (0.41) | TSHRCYP2D6CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460748-A | Process for crosslinking and, if desired, foaming natural or synthetic homo- and/or copolymers | LUPEROX GMBH (DE) | 1984-07-17 | — | — | US | disclosed |