Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10806286 | 0.99 | DRD2 (0.51) | DRD2HTR2ACCR5CCR1SIGMAR1 | |
| SCHEMBL10804285 | 0.92 | HTR2A (0.50) | DRD2HTR2ACCR5CCR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10811623 | 0.91 | HTR2A (0.49) | DRD2HTR2ACCR5SIGMAR1OPRL1 | |
| SCHEMBL11058087 | 0.86 | DRD2 (0.58) | DRD2HTR2ACCR5CCR1OPRL1 | |
| Oxalic Acid SCHEMBL10802865 | 0.82 | DRD2 (0.53) | DRD2CCR5CCR1KCNH2 | |
| SCHEMBL11254741 | 0.79 | DRD2 (0.80) | DRD2HTR2ASIGMAR1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11246163 | 0.79 | DRD2 (0.57) | DRD2HTR2ASIGMAR1HTR1ADRD3 | |
| SCHEMBL1789621 | 0.79 | DRD2 (0.56) | DRD2HTR2ACCR5CCR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11543880 | 0.78 | DRD2 (0.78) | DRD2HTR2ASIGMAR1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11545655 | 0.78 | DRD2 (0.54) | DRD2HTR2ACCR5CCR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452802-A | Antihypertensive spiro[benzofuran-azalkanes] | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-06-05 | — | — | US | claimed |