Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846940 | 0.95 | USP2 (0.45) | KDM4EHPGDUSP2SMN1; SMN2PKM | |
| SCHEMBL15740339 | 0.95 | USP2 (0.45) | KDM4EHPGDUSP2SMN1; SMN2PKM | |
| SCHEMBL14196079 | 0.95 | USP2 (0.45) | KDM4EHPGDUSP2SMN1; SMN2PKM | |
| SCHEMBL11061356 | 0.89 | KDM4E (0.43) | KDM4EALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL13102163 | 0.83 | KMT2A (0.45) | KDM4EALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL2239461 | 0.83 | KMT2A (0.45) | KDM4EALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL15671149 | 0.83 | USP2 (0.50) | KDM4EALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL22876904 | 0.82 | ANPEP (0.42) | HPGDUSP2SMN1; SMN2PKMTP53 | |
| SCHEMBL11064200 | 0.82 | HPGD (0.44) | KDM4EALDH1A1HPGDUSP2SMN1; SMN2 | |
| Bromide SCHEMBL15671179 | 0.81 | KMT2A (0.50) | KDM4EALDH1A1HPGDUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |