Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846940 | 1.00 | USP2 (0.45) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL14196079 | 1.00 | USP2 (0.45) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL11061885 | 0.95 | KDM4E (0.41) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL13102163 | 0.89 | KMT2A (0.45) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL2239461 | 0.89 | KMT2A (0.45) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL15671149 | 0.88 | USP2 (0.50) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| Bromide SCHEMBL15671179 | 0.86 | KMT2A (0.50) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL11061356 | 0.83 | KDM4E (0.43) | USP2SMN1; SMN2HPGDKDM4EPKM | |
| SCHEMBL10151332 | 0.81 | ANPEP (0.46) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL11413505 | 0.81 | KMT2A (0.46) | USP2SMN1; SMN2TP53HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328329-A1 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | American University of Cairo (EG) | 2015-11-19 | — | — | US | disclosed |
| WO-2014081856-A2 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | AZZAZY HASSAN (EG) | 2014-05-30 | — | — | WO | disclosed |