Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061997 | 1.00 | MAOB (0.54) | MAOBMAOACYP1A2HRH3GPR84 | |
| SCHEMBL10479884 | 0.98 | MAOB (0.53) | MAOBMAOACYP1A2HRH3GPR84 | |
| SCHEMBL10479882 | 0.98 | MAOB (0.53) | MAOBMAOACYP1A2HRH3GPR84 | |
| SCHEMBL10717200 | 0.95 | MAOB (0.50) | MAOBMAOACYP1A2HRH3GPR84 | |
| SCHEMBL11062065 | 0.94 | MAOA (0.53) | MAOBMAOACYP1A2HRH3LMNA | |
| SCHEMBL11062059 | 0.94 | MAOA (0.53) | MAOBMAOACYP1A2HRH3LMNA | |
| SCHEMBL11064284 | 0.93 | MAOA (0.51) | MAOBMAOAHRH3LMNASPHK1 | |
| SCHEMBL10479657 | 0.93 | MAOA (0.51) | MAOBMAOACYP1A2HRH3LMNA | |
| SCHEMBL11064280 | 0.93 | MAOA (0.51) | MAOBMAOAHRH3LMNASPHK1 | |
| SCHEMBL10479654 | 0.93 | MAOA (0.51) | MAOBMAOACYP1A2HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439015-A | Disubstituted ethanes | HOFFMANN-LA ROCHE INC. (US) | 1984-03-27 | — | — | US | disclosed |