Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059589 | 0.72 | — | — | |
| SCHEMBL21149860 | 0.68 | ABCB11 (0.35) | ABCB11LMNAPTGS1ALDH1A1PKM | |
| SCHEMBL22556184 | 0.68 | ABCB11 (0.35) | ABCB11LMNAPTGS1ALDH1A1PKM | |
| SCHEMBL22556185 | 0.68 | ABCB11 (0.35) | ABCB11LMNAPTGS1ALDH1A1PKM | |
| SCHEMBL31509116 | 0.68 | SMN1; SMN2 (0.39) | ABCB11LMNAPTGS1FNTAPGGT1B | |
| SCHEMBL24480551 | 0.68 | ABCB11 (0.35) | ABCB11LMNAPTGS1ALDH1A1PKM | |
| SCHEMBL9459719 | 0.68 | SMN1; SMN2 (0.39) | ABCB11LMNAPTGS1FNTAPGGT1B | |
| SCHEMBL13993771 | 0.68 | MEN1 (0.35) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4753888 | 0.67 | — | — | |
| SCHEMBL5138206 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432378-A | ORGANOLEPTIC; TOBACCO; FOODS; DETERGENTS; COSMETICS | FRITZSCHE, DODGE & OLCOTT, INC. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4326996-A | FOR PERFUMES | FRITZSCHE DODGE & OLCOTT INC. (US) | 1982-04-27 | — | — | US | disclosed |