SCHEMBL11062044

SCHEMBL11062044

CC(=O)CCCC(=O)OC(C)C

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
TSHR P16473 4/20 0.44
ALDH1A1 P00352 4/20 0.39
GAA P10253 1/20 0.39
EPHX2 P34913 1/20 0.39
MAPT P10636 3/20 0.38
MAPK1 P28482 1/20 0.38
ACHE P22303 1/20 0.38
PAOX Q6QHF9 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
P2RY12 Q9H244 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18619 0.91 LMNA (0.71) LMNATSHRALDH1A1GAAEPHX2
SCHEMBL811107 0.86 LMNA (0.54) LMNATSHRALDH1A1GAAMAPT
SCHEMBL15391 0.85 LMNA (0.78) LMNATSHRALDH1A1GAAEPHX2
SCHEMBL8104259 0.85 LMNA (0.78) LMNATSHRALDH1A1GAAEPHX2
Acetic Acid SCHEMBL28197988 0.84 LMNA (0.69) LMNATSHRALDH1A1GAAEPHX2
SCHEMBL11816713 0.84 LMNA (0.52) LMNATSHRALDH1A1GAAEPHX2
SCHEMBL6578392 0.84 LMNA (0.53) LMNATSHRALDH1A1GAAEPHX2
SCHEMBL10788600 0.83 LMNA (0.83) LMNATSHRALDH1A1GAAEPHX2
SCHEMBL495594 0.83 LMNA (0.83) LMNATSHRALDH1A1GAAEPHX2
SCHEMBL9216453 0.83 LMNA (0.83) LMNATSHRALDH1A1GAAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108863796-A A kind of method that liquid phase catalytic oxidation lactate prepares pyruvate 大连理工大学 2018-11-23 CN claimed
CN-105682866-B Shave care composition for liquid dispensing razors 吉列有限责任公司 2019-11-12 CN disclosed
CN-110403833-A For enhancing the composition and method of the local application of alkaline beneficial agent JOHNSON & JOHNSON CONSUMER INC 2019-11-05 CN disclosed
CN-110294734-A A kind of preparation method of 2- aminothiophene -3,4- dicarboxylic acid derivatives 上海吉奉生物科技有限公司 2019-10-01 CN disclosed
CN-110234623-A Solution containing dialkylzinc and dialkylzinc partial hydrolysate, and method for producing zinc oxide thin film using same 东曹精细化工株式会社 2019-09-13 CN disclosed
CN-106456476-B Compositions and methods for enhancing topical application of alkaline benefit agents 强生消费者公司 2019-08-27 CN disclosed
CN-110099714-A Microneedle array and its preparation and application 强生消费者公司 2019-08-06 CN disclosed
CN-109843907-A Recombinate Microcystin production 新南创新有限公司 2019-06-04 CN disclosed
CN-109789056-A Kits and methods for local delivery of beneficial effects 强生消费者公司 2019-05-21 CN disclosed
CN-105848640-B Topical gel compositions comprising polycaprolactone polymers and methods for enhancing topical application of benefit agents 强生消费者公司 2019-03-29 CN disclosed
CN-107810093-A Portable disposable fluid distribution hair removal device 吉列有限责任公司 2018-03-16 CN disclosed
CN-107771071-A Multilayer topically applied article for providing benefit to skin 强生消费者公司 2018-03-06 CN disclosed
CN-107771070-A Method for providing a beneficial effect to skin 强生消费者公司 2018-03-06 CN disclosed
CN-107548302-A Viscosity building compositions for personal care products 奥麒个人护理产品有限合伙公司 2018-01-05 CN disclosed
CN-106660221-A DISPOSABLE FLUID DISPENSING HAIR REMOVAL DEVICE 吉列有限公司 2017-05-10 CN disclosed
CN-106536136-A Disposable fluid dispensing hair removal device 吉列有限公司 2017-03-22 CN disclosed
CN-106456476-A Compositions and methods for enhancing topical application of alkaline benefit agents 强生消费者公司 2017-02-22 CN disclosed
CN-106456467-A Compositions and methods for enhancing topical application of color cosmetic 强生消费者公司 2017-02-22 CN disclosed
US-4431848-A Preparation of resorcinol and substituted resorcinols by liquid-phase dehydrogenation of 1,3-cyclic diones derived by vapor-phase cyclization of delta-keto carboxylic acid esters KOPPERS COMPANY, INC. (US) 1984-02-14 US disclosed
US-4399310-A Preparation of 1,3-cyclic diones by vapor phase cyclization of delta-keto carboxylic acid esters utilizing carrier condensable under ambient conditions KOPPERS COMPANY, INC. (US) 1983-08-16 US disclosed