Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778023 | 1.00 | ALOX5 (0.36) | ALOX5PTGS2TYRHTR2ATSHR | |
| SCHEMBL11069561 | 0.91 | ALOX5 (0.40) | ALOX5PTGS2TYRHTR2ATSHR | |
| SCHEMBL9719739 | 0.85 | ALOX5 (0.33) | ALOX5PTGS2TYRHTT | |
| SCHEMBL9576113 | 0.77 | ALOX5 (0.41) | ALOX5PTGS2TYRHTR2ATSHR | |
| SCHEMBL31601473 | 0.77 | ALOX5 (0.34) | ALOX5PTGS2TYRTP53CYP3A4 | |
| SCHEMBL28898243 | 0.74 | ALOX5 (0.38) | ALOX5PTGS2TYRHTR2ATSHR | |
| SCHEMBL130578 | 0.72 | TYR (0.44) | ALOX5PTGS2TYRTSHRMEN1 | |
| SCHEMBL29358468 | 0.72 | TYR (0.44) | ALOX5PTGS2TYRTSHRMEN1 | |
| SCHEMBL10790741 | 0.72 | TYR (0.44) | ALOX5PTGS2TYRTSHRMEN1 | |
| SCHEMBL10883586 | 0.72 | TYR (0.44) | ALOX5PTGS2TYRTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456717-A | PHOSPHITES AND SILOXANE-OXETANE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | disclosed |