Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350793 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16182817 | 0.90 | ELANE (0.57) | SMN1; SMN2KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16182754 | 0.90 | ELANE (0.57) | SMN1; SMN2KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8835845 | 0.90 | ELANE (0.57) | SMN1; SMN2KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8835839 | 0.90 | ELANE (0.57) | SMN1; SMN2KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7268906 | 0.85 | ELANE (0.54) | SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL544782 | 0.84 | ELANE (0.64) | SMN1; SMN2KDM4ECYP3A4NPC1RAB9A | |
| SCHEMBL6811022 | 0.84 | ELANE (0.64) | SMN1; SMN2KDM4ECYP3A4NPC1RAB9A | |
| SCHEMBL17627813 | 0.84 | KDM4E (0.43) | SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16182767 | 0.83 | ELANE (0.50) | SMN1; SMN2KDM4ECYP3A4ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444868-A | CONTAINING STYRYL-TYPE NITROGEN-HETEROCYCLE RESIDUE POLYMER AND ACID | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1984-04-24 | — | — | US | disclosed |