Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490151 | 0.89 | ALDH1A1 (0.68) | LMNAKDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL27372394 | 0.82 | TSHR (0.68) | LMNAKDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2637708 | 0.82 | ALDH1A1 (0.57) | LMNAKDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL27404873 | 0.81 | ALDH1A1 (0.66) | LMNAALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL162806 | 0.80 | HDAC1 (0.62) | LMNAKDM4EALDH1A1L3MBTL1TDP1 | |
| SCHEMBL24404099 | 0.80 | ALDH1A1 (0.56) | LMNAKDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL15593871 | 0.80 | MAPT (0.59) | CA12CA7CA9CA14CES1 | |
| SCHEMBL9404068 | 0.80 | MAPT (0.54) | LMNAKDM4EALDH1A1TDP1CA12 | |
| SCHEMBL3286619 | 0.80 | HDAC3 (0.61) | LMNAALDH1A1TSHRL3MBTL1TDP1 | |
| SCHEMBL10030999 | 0.79 | ALDH1A1 (0.58) | LMNAKDM4EALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431848-A | Preparation of resorcinol and substituted resorcinols by liquid-phase dehydrogenation of 1,3-cyclic diones derived by vapor-phase cyclization of delta-keto carboxylic acid esters | KOPPERS COMPANY, INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4399310-A | Preparation of 1,3-cyclic diones by vapor phase cyclization of delta-keto carboxylic acid esters utilizing carrier condensable under ambient conditions | KOPPERS COMPANY, INC. (US) | 1983-08-16 | — | — | US | disclosed |