Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.62 |
| ▸ | MAOA | P21397 | 11/20 | 0.54 |
| ▸ | MAOB | P27338 | 11/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068620 | 0.92 | PDE3B (0.62) | PDE3BPDE3AMAOAMAOBROCK2 | |
| SCHEMBL11066234 | 0.86 | PDE3B (0.68) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL11067615 | 0.85 | PDE3B (0.67) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL11063117 | 0.85 | PDE3B (0.64) | PDE3BPDE3AMAOAMAOBROCK2 | |
| SCHEMBL11061330 | 0.84 | PDE3B (0.69) | PDE3BPDE3AMAOAMAOBROCK2 | |
| SCHEMBL11058585 | 0.84 | MAOA (0.67) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL11067828 | 0.83 | PDE3B (0.75) | PDE3BPDE3A | |
| SCHEMBL11061870 | 0.83 | PDE3B (0.75) | PDE3BPDE3A | |
| SCHEMBL11068276 | 0.82 | PDE3B (0.57) | PDE3BPDE3AMAOAMAOBROCK2 | |
| SCHEMBL11603017 | 0.81 | PDE3B (0.63) | PDE3BPDE3AMAOAMAOBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |