Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496720 | 1.00 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967421 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL773307 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967398 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL6227681 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967484 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL9007085 | 0.92 | HSPA5 (0.38) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL10825679 | 0.87 | HMGCR (0.37) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967509 | 0.86 | HSPA5 (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL1509707 | 0.86 | HSPA5 (0.40) | HMGCRNR1I2HSPA5LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440672-A | SPIRO(INDOLINE-2,3'-(3'H)-NAPHTN(1,2-B)(1,4) OXAZINES), ULTRAVIOLET STABILIZER | AMERICAN OPTICAL CORPORATION (US) | 1984-04-03 | — | — | US | claimed |
| US-20160060398-A1 | METHOD OF MANUFACTURING CATIONIC POLYMERIZATION RESIN WITH ENHANCED UV STABILITY AND CATIONIC POLYMERIZATION RESIN MANUFACTURED BY THE SAME | Solip Tech Co., Ltd. (KR) | 2016-03-03 | — | — | US | disclosed |