Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062891 | 1.00 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967421 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL773307 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967398 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL6227681 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967484 | 0.97 | HMGCR (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL9007085 | 0.92 | HSPA5 (0.38) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL10825679 | 0.87 | HMGCR (0.37) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL5967509 | 0.86 | HSPA5 (0.40) | HMGCRNR1I2HSPA5LMNARECQL | |
| SCHEMBL1509707 | 0.86 | HSPA5 (0.40) | HMGCRNR1I2HSPA5LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310771-A | Ultraviolet resistance, hindered amines, metal phosphonates, triazines | PHILLIPS PETROLEUM COMPANY (US) | 1994-05-10 | — | — | US | claimed |
| US-4076689-A | ZINC OXIDE, A ZINC DIHYDROCARBYLDITHIOCARBAMATE,A NICKEL BIS(HYDROXYPHENYL-ALKYLPHOSPHONATE) | PHILLIPS PETROLEUM COMPANY (US) | 1978-02-28 | — | — | US | claimed |
| US-8106135-B2 | Polyethersulfone compositions with high heat and good impact resistance | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-01-31 | — | — | US | disclosed |
| US-20070117962-A1 | High heat polyethersulfone compositions | GENERAL ELECTRIC COMPANY (US) | 2007-05-24 | — | — | US | disclosed |
| US-20070049724-A1 | POLYETHERSULFONE COMPOSITIONS WITH HIGH HEAT AND GOOD IMPACT RESISTANCE | GENERAL ELECTRIC COMPANY (US) | 2007-03-01 | — | — | US | disclosed |
| US-4291093-A | Stabilized polyolefin substrate overcoated with an ethoxylated lubricant and a phosphate ester | PHILLIPS PETROLEUM CO. (US) | 1981-09-22 | — | — | US | disclosed |
| EP-0027926-A1 | Degradation resistant polyolefin articles and process for making same | PHILLIPS PETROLEUM COMPANY (US) | 1981-05-06 | — | — | EP | disclosed |
| US-4166814-A | LIGHT STABILIZATION OF POLYMERS | CIBA-GEIGY CORPORATION (US) | 1979-09-04 | — | — | US | disclosed |
| US-4113914-A | BLOCK POLYMER OF SYTRENE AND BUTADIENE OR ISOPRENE | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4076689-A | ZINC OXIDE, A ZINC DIHYDROCARBYLDITHIOCARBAMATE,A NICKEL BIS(HYDROXYPHENYL-ALKYLPHOSPHONATE) | PHILLIPS PETROLEUM COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-3991130-A | Organo-nickel salts as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |