Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24534624 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CTSLCTSBCTSKSIGMAR1 | |
| SCHEMBL10946417 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CTSLCTSBCTSKSIGMAR1 | |
| SCHEMBL25948326 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CTSLCTSBCTSKSIGMAR1 | |
| SCHEMBL21423866 | 0.91 | CHRM1 (0.53) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL21103823 | 0.88 | HSD17B10 (0.50) | ALDH1A1SIGMAR1KMT2AL3MBTL1NPC1 | |
| SCHEMBL20855479 | 0.88 | MEN1 (0.54) | ALDH1A1KMT2AMEN1NPSR1LMNA | |
| SCHEMBL22648518 | 0.87 | MEN1 (0.59) | ALDH1A1KMT2AMEN1NPSR1LMNA | |
| SCHEMBL25265146 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL13049037 | 0.87 | MEN1 (0.59) | ALDH1A1KMT2AMEN1NPSR1LMNA | |
| SCHEMBL25190840 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452990-A | TREATMENT OF SENILITY, AMNESIA AND MOTIVATION | WARNER-LAMBERT COMPANY (US) | 1984-06-05 | — | — | US | disclosed |