Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5485542 | 0.98 | SIGMAR1 (0.52) | SIGMAR1CHRM5CHRM3CYP1A2PABPC1 | |
| SCHEMBL23835774 | 0.84 | ATM (0.50) | SIGMAR1PABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL11064005 | 0.82 | SIGMAR1 (0.51) | SIGMAR1CHRM5CHRM3CYP1A2ATM | |
| SCHEMBL11066704 | 0.82 | SIGMAR1 (0.49) | SIGMAR1CHRM5CHRM3CYP1A2KDM4E | |
| SCHEMBL27536506 | 0.79 | SIGMAR1 (0.46) | SIGMAR1CHRM5CHRM3CYP1A2MEN1 | |
| SCHEMBL24069101 | 0.79 | CHRM5 (0.46) | SIGMAR1CHRM5CHRM3CYP1A2CA2 | |
| SCHEMBL23866564 | 0.78 | KDM4E (0.55) | SIGMAR1CYP1A2PABPC1APOBEC3AEIF4H | |
| SCHEMBL23866568 | 0.78 | KDM4E (0.55) | SIGMAR1CYP1A2PABPC1APOBEC3AEIF4H | |
| SCHEMBL21661626 | 0.78 | KDM4E (0.55) | SIGMAR1CYP1A2PABPC1APOBEC3AEIF4H | |
| SCHEMBL6678936 | 0.78 | SIGMAR1 (0.58) | SIGMAR1CHRM5CHRM3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478838-A | VASODILATOR AGENTS | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1984-10-23 | — | — | US | disclosed |
| EP-0083712-A1 | 1-(3,4,5-Trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives and a process for the preparation thereof | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1983-07-20 | — | — | EP | disclosed |