Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 17/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068389 | 1.00 | TBXAS1 (0.81) | TBXAS1MAPTRXFP1 | |
| SCHEMBL11062457 | 1.00 | TBXAS1 (0.81) | TBXAS1MAPTRXFP1 | |
| SCHEMBL11067275 | 1.00 | TBXAS1 (0.81) | TBXAS1MAPTRXFP1 | |
| SCHEMBL11058790 | 1.00 | TBXAS1 (0.81) | TBXAS1MAPTRXFP1 | |
| SCHEMBL11066764 | 0.99 | TBXAS1 (0.81) | TBXAS1MAPTRXFP1 | |
| SCHEMBL11067276 | 0.94 | TBXAS1 (0.83) | TBXAS1 | |
| SCHEMBL1009589 | 0.90 | TBXAS1 (1.00) | TBXAS1MAPTRXFP1 | |
| SCHEMBL607494 | 0.90 | TBXAS1 (1.00) | TBXAS1MAPTRXFP1 | |
| SCHEMBL7443753 | 0.90 | TBXAS1 (1.00) | TBXAS1MAPTRXFP1 | |
| SCHEMBL16116694 | 0.90 | TBXAS1 (1.00) | TBXAS1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |