Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068041 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL8356665 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL8356661 | 0.83 | CA12 (0.46) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL9416688 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL2782787 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL11385025 | 0.80 | SOAT1 (0.41) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL11228703 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL8172575 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL2169170 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10HPGDGAA | |
| SCHEMBL41804 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436661-A | INTERMEDIATES FOR PENICILLIN ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4431588-A | PENACILLINS | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |