Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EIF4E | P06730 | 5/20 | 0.44 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371711 | 0.86 | GFER (0.67) | GFERKDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL9028719 | 0.85 | EIF4E (0.49) | GFERKDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL11159354 | 0.81 | ABL1 (0.55) | GFERKDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL203617 | 0.81 | GFER (1.00) | GFERKDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL11068684 | 0.80 | ABL1 (0.45) | GFERKDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL11158204 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1RAB9ANPC1GAA | |
| SCHEMBL11070222 | 0.79 | ABL1 (0.44) | GFERKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL1423116 | 0.79 | GFER (0.66) | GFERKDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL3372678 | 0.79 | GFER (0.71) | GFERKDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL14060922 | 0.76 | GFER (0.58) | GFERKDM4EALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431652-A | UROGENITAL DISORDERS; KIDNEY AND BLADDER STONES; PROPHYLAXIS; OXIDASE ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1984-02-14 | — | — | US | disclosed |