Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | EIF4E | P06730 | 13/20 | 0.43 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070222 | 0.87 | ABL1 (0.44) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11064024 | 0.80 | GFER (0.68) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11071752 | 0.79 | ABL1 (0.46) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL9028719 | 0.79 | EIF4E (0.49) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11158204 | 0.77 | KDM4E (0.51) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11159354 | 0.75 | ABL1 (0.55) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL14997991 | 0.71 | RAB9A (0.50) | KDM4ENPC1RAB9AGFERALDH1A1 | |
| SCHEMBL17609932 | 0.70 | KDM4E (0.53) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL22815610 | 0.70 | EIF4E (0.49) | ABL1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL22815574 | 0.70 | KDM4E (0.49) | ABL1KDM4EMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431652-A | UROGENITAL DISORDERS; KIDNEY AND BLADDER STONES; PROPHYLAXIS; OXIDASE ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1984-02-14 | — | — | US | disclosed |