Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779569 | 0.81 | TSHR (0.36) | TSHRALDH1A1HPGDMEN1POLB | |
| SCHEMBL35668 | 0.81 | ADRB2 (0.45) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL6448719 | 0.78 | ADRB2 (0.43) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL31482751 | 0.78 | ADRB2 (0.43) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL1538446 | 0.78 | ADRB2 (0.43) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL37127 | 0.78 | — | — | |
| SCHEMBL9147450 | 0.76 | ADRB2 (0.41) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL9147120 | 0.76 | ADRB2 (0.41) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL9149058 | 0.76 | ADRB2 (0.41) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL18696055 | 0.76 | TSHR (0.38) | TSHRALDH1A1HPGDADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490526-A | ORGANOSILANE MODIFIERS | DYNAMIT NOBEL AG (DE) | 1984-12-25 | — | — | US | disclosed |