Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.63 |
| ▸ | ATP4B | P51164 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063974 | 0.90 | ATP4A (0.63) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11066583 | 0.90 | ATP4A (0.77) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11094486 | 0.89 | ATP4A (0.58) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11100335 | 0.88 | ATP4A (0.64) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11069836 | 0.88 | ATP4A (0.82) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2192635 | 0.86 | ATP4A (0.83) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11070692 | 0.86 | ATP4A (0.61) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| Iodomethane SCHEMBL11064047 | 0.84 | ATP4A (0.58) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11069321 | 0.83 | GUCY1B2 (0.55) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2195617 | 0.82 | ATP4A (0.81) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450164-A | ANTIULCER AND ANTISECRETORY AGENTS | SCHERING CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |
| EP-0033094-A1 | Imidazo(1,2-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |