Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147317 | 0.88 | APEX1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL11486450 | 0.86 | NPC1 (0.37) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL4151776 | 0.84 | ALDH1A1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6742007 | 0.82 | NPC1 (0.39) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL11494047 | 0.81 | NPC1 (0.33) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL11569511 | 0.79 | ALDH1A1 (0.42) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29026606 | 0.78 | APEX1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29444201 | 0.78 | APEX1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30402913 | 0.78 | APEX1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL28451316 | 0.78 | ALDH1A1 (0.41) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474914-A | Ortho-alkylated phenyl phosphonites and stabilized organic compositions | CIBA-GEIGY CORPORATION (US) | 1984-10-02 | — | — | US | claimed |
| US-4406842-A | PHOTOSTABILITY FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1983-09-27 | — | — | US | claimed |
| US-4474914-A | Ortho-alkylated phenyl phosphonites and stabilized organic compositions | CIBA-GEIGY CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| US-4406842-A | PHOTOSTABILITY FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1983-09-27 | — | — | US | disclosed |