Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073822 | 0.93 | KCNH2 (0.54) | KCNH2MAOAMAOBSCN1ASCN5A | |
| SCHEMBL11069966 | 0.87 | DRD4 (0.63) | KCNH2MAOAMAOBGAA | |
| SCHEMBL2017735 | 0.87 | KCNH2 (0.78) | KCNH2HTR7LMNA | |
| SCHEMBL2020554 | 0.87 | KCNH2 (0.78) | KCNH2HTR7LMNA | |
| SCHEMBL2017738 | 0.87 | KCNH2 (0.78) | KCNH2HTR7LMNA | |
| SCHEMBL15586801 | 0.86 | DRD4 (0.64) | KCNH2KDM1AMAOAMAOBSCN1A | |
| SCHEMBL15586823 | 0.86 | DRD4 (0.64) | KCNH2KDM1AMAOAMAOBSCN1A | |
| SCHEMBL2020104 | 0.85 | KCNH2 (0.82) | KCNH2HTR7LMNA | |
| SCHEMBL2018563 | 0.85 | KCNH2 (0.82) | KCNH2HTR7LMNA | |
| SCHEMBL2018560 | 0.85 | KCNH2 (0.82) | KCNH2HTR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |