Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | OGT | O15294 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071360 | 0.93 | MAOA (0.69) | DRD4KCNH2GAAMAOAMAOB | |
| SCHEMBL10572504 | 0.88 | KCNH2 (0.70) | KCNH2GAAMAOAMAOBTSHR | |
| SCHEMBL11064138 | 0.87 | KCNH2 (0.64) | KCNH2GAAMAOAMAOB | |
| SCHEMBL15586801 | 0.84 | DRD4 (0.64) | DRD4KCNH2MAOAMAOBDRD2 | |
| SCHEMBL15586823 | 0.84 | DRD4 (0.64) | DRD4KCNH2MAOAMAOBDRD2 | |
| SCHEMBL2018563 | 0.84 | KCNH2 (0.82) | KCNH2KMT2ADRD2 | |
| SCHEMBL2020104 | 0.84 | KCNH2 (0.82) | KCNH2KMT2ADRD2 | |
| SCHEMBL2018560 | 0.84 | KCNH2 (0.82) | KCNH2KMT2ADRD2 | |
| SCHEMBL2023161 | 0.84 | KCNH2 (0.62) | KCNH2GAAMAOAMAOB | |
| SCHEMBL2023159 | 0.84 | KCNH2 (0.62) | KCNH2GAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |