Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064346 | 1.00 | CYP4A11 (0.49) | CYP4A11RARBCYP4F2MAPTMEN1 | |
| SCHEMBL11060365 | 0.96 | CYP4A11 (0.52) | CYP4A11CYP4F2MAPTMEN1KMT2A | |
| SCHEMBL11060372 | 0.96 | CYP4A11 (0.52) | CYP4A11CYP4F2MAPTMEN1KMT2A | |
| SCHEMBL11058919 | 0.95 | CYP4A11 (0.51) | CYP4A11RARBCYP4F2MAPTSMN1; SMN2 | |
| SCHEMBL11065191 | 0.95 | CYP4A11 (0.51) | CYP4A11RARBCYP4F2MAPTSMN1; SMN2 | |
| SCHEMBL11065186 | 0.95 | CYP4A11 (0.51) | CYP4A11RARBCYP4F2MAPTSMN1; SMN2 | |
| SCHEMBL11058923 | 0.95 | CYP4A11 (0.51) | CYP4A11RARBCYP4F2MAPTSMN1; SMN2 | |
| SCHEMBL11061983 | 0.92 | CYP4A11 (0.54) | CYP4A11CYP4F2MAPTMEN1ALDH1A1 | |
| SCHEMBL11061985 | 0.92 | CYP4A11 (0.54) | CYP4A11CYP4F2MAPTMEN1ALDH1A1 | |
| SCHEMBL11061034 | 0.91 | CYP4A11 (0.49) | CYP4A11RARBCYP4F2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439015-A | Disubstituted ethanes | HOFFMANN-LA ROCHE INC. (US) | 1984-03-27 | — | — | US | disclosed |